New Concepts, Concerns, and Creations in Acne
Laboratory monitoring for patients on isotretinoin should include creatinine kinase in athletic males and the more liver-specific gamma glutamyltransferase. There is mounting evidence that acne pathophysiology includes a barrier defect and subsequent microbiome disruption. Avoidance of acne scars with early and aggressive treatment is a more efficient and cost-effective option than subsequent treatment. Laser and light treatments for acne and acne scars are plentiful but poorly supported by evidence-based medicine. The acne pipeline is rich with new chemical entities, new formulations, and combinations of older agents. The gold standard for acne therapy may be changing its face.
Keywords:Acne, Acne scarring, Microbiome, Creatine kinase, Acne pipeline, Gamma glutamyltransferase
Autor / Fonte:Justin W Marson, Hilary E Baldwin Dermatologic Clinics 2019, 37 (1): 1-9