Multi-dimensional reliability assessment of fractal signature analysis in an outpatient sports medicine population
The aim of this study has been to test reproducibility of fractal signature analysis (FSA) in a young, active patient population taking into account several parameters including intra- and inter-reader placement of regions of interest (ROIs) as well as various aspects of projection geometry.
In total, 685 patients were included (135 athletes and 550 non-athletes, 18 to 36 years old). Regions of interest (ROI) were situated beneath the medial tibial plateau. The reproducibility of texture parameters was evaluated using intraclass correlation coefficients (ICC). Multi-dimensional assessment included 1. Anterior-posterior (A.P.) vs. posterior-anterior (P.A.) (Lyon-Schuss technique) views on 102 knees, 2. Unilateral (single knee) vs. bilateral (both knees) acquisition on 27 knees (acquisition technique otherwise identical; same A.P. or P.A. view) 3. Repetition of the same image acquisition on 46 knees (same A.P. or P.A. view, and same unitlateral or bilateral acquisition) and 4. Intra- and inter-reader reliability with repeated placement of the ROIs in the subchondral bone area on 99 randomly chosen knees.
ICC values on the reproducibility of texture parameters for A.P. vs. P.A. image acquisitions for horizontal and vertical dimensions combined were 0.72 (95% confidence interval (CI) 0.70-0.74) ranging from 0.47 to 0.81 for the different dimensions. For unilateral vs. bilateral image acquisitions, the ICCs were 0.79 (95% CI 0.76-0.82) ranging from 0.55 to 0.88. For the repetition of the identical view, the ICCs were 0.82 (95% CI 0.80-0.84) ranging from 0.67 to 0.85. Intra-reader reliability was 0.93 (95% CI 0.92-0.94) and inter-observer reliability was 0.96 (95% CI 0.88-0.99). A decrease in reliability was observed with increasing voxel sizes Our study confirms excellent intra and inter-reader reliability for FSA, however, results seem to be affected by acquisition technique, which has not been previously recognized.
- Fractal signature analysis;
Copyright © 2015 Published by Elsevier GmbH
Note to users: Accepted manuscripts are Articles in Press that have been peer reviewed and accepted for publication by the Editorial Board of this publication. They have not yet been copy edited and/or formatted in the publication house style, and may not yet have the full ScienceDirect functionality, e.g., supplementary files may still need to be added, links to references may not resolve yet etc. The text could still change before final publication.
Although accepted manuscripts do not have all bibliographic details available yet, they can already be cited using the year of online publication and the DOI, as follows: author(s), article title, Publication (year), DOI. Please consult the journal's reference style for the exact appearance of these elements, abbreviation of journal names and use of punctuation.
When the final article is assigned to an volumes/issues of the Publication, the Article in Press version will be removed and the final version will appear in the associated published volumes/issues of the Publication. The date the article was first made available online will be carried over.
Autor / Fonte:Mohamed Jarraya, Ali Guermazi, Jingbo Niu, Jeffrey Duryea, John A Lynch, Frank W Roemer Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft 2015 August 20, 202: 57-60