Effects of vitamin D supplementation on pulmonary function in postmenopausal women following an aquatic exercise program



This study sought to investigate the effects of vitamin D supplementation and aquatic exercise on pulmonary function in postmenopausal women.

Materials and methods

This prospective and controlled study included 104 women (62 ± 6.5 years) divided into three groups: a control group lacking vitamin D and calcium supplementation which remained sedentary (CG; n = 17); a control group receiving vitamin D and calcium supplementation which remained sedentary (CDG, n = 33); and a group that completed aquatic exercises three times a week and received vitamin D and calcium supplementation (DTG, n = 54). Data before and after 6 months of the study were analyzed, including serum 25-hydroxyvitamin D (25(OH)D) and calcium concentrations, peak expiratory flow (PEF), forced vital capacity (FVC), and cirtometry.


We observed significant increases in 25(OH)D concentrations in CDG (52.9 ± 2.4 to 69.1 ± 2.2; nmol/L; p < 0.0001) and DTG groups (55.5 ± 3 to 71.5 ± 3 nmol/L; p < 0.0001). PEF increased by 7 ± 2% (p = 0.0080) in CDG group and 11 ± 2% (p < 0.0001) in DTG group, whereas FVC increased by 7 ± 2% (p = 0.0016) in the CDG group and 10 ± 2% (p < 0.0001) in the DTG group, whereas CG had no changes in any of these parameters. The increment value of cirtometry in DTG group (+43 ± 3%) were significantly (p < 0.0001) higher than those in CG (−4 ± 8%) and CDG (+4 ± 9%) groups.


Our data suggest that vitamin D supplementation improves pulmonary function parameters in postmenopausal women.

Key words: Spirometry; cirtometry; cholecalciferol; postmenopause 


Autor / Fonte:Rodrigo Nolasco, Linda D F Moreira, Danilo S Bocalini, Fernanda C A O Fronza, Rosangela Villa Marin, Marise Lazaretti-Castro Archives of Endocrinology and Metabolism 2016 October 10
Link: http://www.scielo.br/pdf/aem/2016nahead/2359-3997-aem-2359-3997000000211.pdf